CENTISORB are intended for use in general soft tissue approximation and /or ligation, including use in ophthalmic surgery, peripheral nerve anastomosis and microsurgery for vessels less than 2mm diameter. The safety and effectiveness of CENTISORB sutures in cardiovascular tissue have not been established.

'Centisorb PnW 2421' refers to a surgical suture, specifically a 'Centisorb' brand absorbable suture with a 'PNW 2421' code, typically indicating a size '1-0' with a 'half-circle reverse cutting' needle, designed for general soft tissue approximation and ligation in various surgical procedures; it is commonly used for deep tissue closure where moderate tensile strength and relatively fast absorption are needed.

In general, surgeons typically use either polypropylene or polydioxanone sutures for fascia, depending on how strong the repair needs to be. Polypropylene is also very common in cardiovascular surgery. Deep dermis closure is with either polyglycolic acid or poliglecaprone 25 sutures.

Monofilament Polypropylene sutures is indicated for use in general soft tissue approximation, ligation including use in cardiovascular, ophthalmic, plastic, neurological surgeries, micro procedures and Hernia repair.

What are the disadvantages of polypropylene sutures?The core of the suture contains less oriented, and weaker, polymer crystals with less tensile strength. This explains why physical damage to the “hardened” outer layer of any polypropylene suture from a stray knot, kinking, or a pinch with forceps will cause early breakage or failure.

Polypropylene suture is a synthetic monofilament suture with greater tensile strength and less tissue adherence compared to nylon. It is commonly used for pull-out subcuticular sutures and running sutures on the face in medical procedures.The core of the suture contains less oriented, and weaker, polymer crystals with less tensile strength. This explains why physical damage to the “hardened” outer layer of any polypropylene suture from a stray knot, kinking, or a pinch with forceps will cause early breakage or failure.

Although these sutures absorb at varying rates, they all usually absorb within four to eight weeks. Nylon, monofilament nonabsorbable sutures (e.g., polypropylene [Prolene]) must eventually be removed. In general, surgeons typically use either polypropylene or polydioxanone sutures for fascia, depending on how strong the repair needs to be. Polypropylene is also very common in cardiovascular surgery. Deep dermis closure is with either polyglycolic acid or poliglecaprone 25 sutures.

Monofilament Polypropylene sutures is indicated for use in general soft tissue approximation, ligation including use in cardiovascular, ophthalmic, plastic, neurological surgeries, micro procedures and Hernia repair. Prolene is a brand of synthetic polypropylene used in monofilament nonabsorbable sutures and meshes. The suture is indicated for skin closure and general soft tissue approximation and ligation. Its advantages include minimal tissue reactivity and durability.